A variational autoencoder trained with priors from canonical pathways increases the interpretability of transcriptome data

• Bin Liu,

  Roles Data curation, Formal analysis, Software, Writing – original draft, Writing – review & editing

  Affiliation Hannover Medical School, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research, Hannover, Lower Saxony, Germany

  https://orcid.org/0000-0003-4311-6698

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• Bodo Rosenhahn,

  Roles Methodology, Supervision

  Affiliation Institut für Informationsverarbeitung (TNT), Leibniz University Hannover, Hannover, Lower Saxony, Germany

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• Thomas Illig,

  Roles Funding acquisition, Supervision

  Affiliations Hannover Medical School, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research, Hannover, Lower Saxony, Germany, Hannover Unified Biobank, Hannover Medical School, Hannover, Lower Saxony, Germany

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• David S. DeLuca

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: DeLuca.David@mh-hannover.de

  Affiliation Hannover Medical School, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research, Hannover, Lower Saxony, Germany

  https://orcid.org/0000-0002-0141-9116

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