Network analysis of toxin production in Clostridioides difficile identifies key metabolic dependencies

• Deborah A. Powers,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliation Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

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• Matthew L. Jenior,

  Roles Methodology, Software, Writing – review & editing

  Affiliation Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, Virginia, United States of America

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• Glynis L. Kolling,

  Roles Supervision, Writing – review & editing

  Affiliation Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, Virginia, United States of America

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• Jason A. Papin

  Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: papin@virginia.edu

  Affiliations Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Biomedical Engineering, School of Engineering, University of Virginia, Charlottesville, Virginia, United States of America

  https://orcid.org/0000-0002-2769-5805

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