A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

• Salim Ghannoum ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: salim.ghannoum@medisin.uio.no (SG); alvaro.kohn-luque@medisin.uio.no (AKL); hesso.farhan@i-med.ac.at (HF)

  ¶‡ These authors share first authorship on this work.

  Affiliation Institute of Basic Medical Sciences, Department of Molecular Medicine, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0003-1455-5835

  ⨯
• Damiano Fantini ,

  Roles Software, Writing – review & editing

  ¶‡ These authors share first authorship on this work.

  Affiliation Department of Urology, Northwestern University, Chicago, Illinois, United States of America

  ⨯
• Muhammad Zahoor,

  Roles Methodology, Writing – review & editing

  Affiliation Institute of Basic Medical Sciences, Department of Molecular Medicine, University of Oslo, Oslo, Norway

  ⨯
• Veronika Reiterer,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Institute of Pathophysiology, Medical University of Innsbruck, Innsbruck, Austria

  ⨯
• Santosh Phuyal,

  Roles Methodology

  Affiliation Institute of Basic Medical Sciences, Department of Molecular Medicine, University of Oslo, Oslo, Norway

  ⨯
• Waldir Leoncio Netto,

  Roles Software, Writing – review & editing

  Affiliation Oslo Centre for Biostatistics and Epidemiology, Faculty of Medicine, University of Oslo, Oslo, Norway

  ⨯
• Øystein Sørensen,

  Roles Software

  Affiliation Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0003-0724-3542

  ⨯
• Arvind Iyer,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Computational Biology, University of Lausanne (UNIL), Lausanne, Switzerland

  https://orcid.org/0000-0002-8247-700X

  ⨯
• Debarka Sengupta,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Computational Biology, Indraprastha Institute of Information Technology, New Delhi, India, Centre for Artificial Intelligence, Indraprastha Institute of Information Technology, Delhi, India

  ⨯
• Lina Prasmickaite,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway

  ⨯
• Gunhild Mari Mælandsmo,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway, Department of Medical Biology, UiT—The Arctic University of Norway, Tromsø, Norway

  ⨯
• Alvaro Köhn-Luque ,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: salim.ghannoum@medisin.uio.no (SG); alvaro.kohn-luque@medisin.uio.no (AKL); hesso.farhan@i-med.ac.at (HF)

  Affiliation Oslo Centre for Biostatistics and Epidemiology, Faculty of Medicine, University of Oslo, Oslo, Norway

  ⨯
• Hesso Farhan

  Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: salim.ghannoum@medisin.uio.no (SG); alvaro.kohn-luque@medisin.uio.no (AKL); hesso.farhan@i-med.ac.at (HF)

  Affiliations Institute of Basic Medical Sciences, Department of Molecular Medicine, University of Oslo, Oslo, Norway, Institute of Pathophysiology, Medical University of Innsbruck, Innsbruck, Austria

  ⨯