Efficient computation of adjoint sensitivities at steady-state in ODE models of biochemical reaction networks

• Polina Lakrisenko,

  Roles Conceptualization, Formal analysis, Investigation, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany, Center for Mathematics, Technische Universität München, Garching, Germany

  https://orcid.org/0000-0002-7626-8420

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• Paul Stapor,

  Roles Conceptualization, Methodology, Software, Writing – review & editing

  Affiliations Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany, Center for Mathematics, Technische Universität München, Garching, Germany

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• Stephan Grein,

  Roles Conceptualization, Methodology, Software, Writing – review & editing

  Affiliation University of Bonn, Life and Medical Sciences Institute, Bonn, Germany

  https://orcid.org/0000-0001-9524-6633

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• Łukasz Paszkowski,

  Roles Software, Writing – review & editing

  Affiliation Simula Research Laboratory, Oslo, Norway

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• Dilan Pathirana,

  Roles Conceptualization, Methodology, Software, Supervision, Writing – review & editing

  Affiliation University of Bonn, Life and Medical Sciences Institute, Bonn, Germany

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• Fabian Fröhlich,

  Roles Software, Writing – review & editing

  Affiliation Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-5360-4292

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• Glenn Terje Lines,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Simula Research Laboratory, Oslo, Norway

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• Daniel Weindl,

  Roles Conceptualization, Funding acquisition, Methodology, Software, Supervision, Writing – review & editing

  Affiliation Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany

  https://orcid.org/0000-0001-9963-6057

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• Jan Hasenauer

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  * E-mail: jan.hasenauer@uni-bonn.de

  Affiliations Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany, University of Bonn, Life and Medical Sciences Institute, Bonn, Germany

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