Computational analysis of 5-fluorouracil anti-tumor activity in colon cancer using a mechanistic pharmacokinetic/pharmacodynamic model

• Chenhui Ma ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  * E-mail: chenhui.ma@case.edu

  Affiliation Department of Electrical, Computer and Systems Engineering, Case Western Reserve University, Cleveland, Ohio, United States of America

  https://orcid.org/0000-0002-7366-7602

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• Alex Almasan,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Evren Gurkan-Cavusoglu

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Electrical, Computer and Systems Engineering, Case Western Reserve University, Cleveland, Ohio, United States of America

  https://orcid.org/0000-0002-9626-0848

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