A machine learning model trained on a high-throughput antibacterial screen increases the hit rate of drug discovery

• A. S. M. Zisanur Rahman,

  Roles Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada

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• Chengyou Liu,

  Roles Data curation, Methodology, Software, Writing – original draft

  Affiliation Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, Manitoba, Canada

  https://orcid.org/0000-0002-2078-9737

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• Hunter Sturm,

  Roles Data curation, Methodology, Software, Writing – review & editing

  Affiliation Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada

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• Andrew M. Hogan,

  Roles Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada

  https://orcid.org/0000-0002-0782-012X

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• Rebecca Davis,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada

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• Pingzhao Hu,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Computer Science, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada

  https://orcid.org/0000-0002-9546-2245

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• Silvia T. Cardona

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Writing – original draft, Writing – review & editing

  * E-mail: silvia.cardona@umanitoba.ca

  Affiliations Department of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Canada

  https://orcid.org/0000-0002-0629-8886

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