Generative and interpretable machine learning for aptamer design and analysis of in vitro sequence selection

• Andrea Di Gioacchino ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors contributed equally to this work and are ordered alphabetically.

  Affiliation Laboratoire de Physique de l’Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, Paris, France

  https://orcid.org/0000-0002-6085-7589

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• Jonah Procyk ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors contributed equally to this work and are ordered alphabetically.

  Affiliation School of Molecular Sciences and Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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• Marco Molari,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft

  Affiliations Laboratoire de Physique de l’Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, Paris, France, Biozentrum, University of Basel, Basel, Switzerland, Swiss Institute of Bioinformatics, Basel, Switzerland

  https://orcid.org/0000-0001-8838-4093

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• John S. Schreck,

  Roles Formal analysis, Methodology

  Affiliation National Center for Atmospheric Research, Computational and Information Systems Laboratory, Boulder, Colorado, United States of America

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• Yu Zhou,

  Roles Methodology

  Affiliation School of Molecular Sciences and Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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• Yan Liu,

  Roles Methodology

  Affiliation School of Molecular Sciences and Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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• Rémi Monasson ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: remi.monasson@phys.ens.fr (RM); simona.cocco@phys.ens.fr (SC); psulc@asu.edu (PŠ)

  Affiliation Laboratoire de Physique de l’Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, Paris, France

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• Simona Cocco ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: remi.monasson@phys.ens.fr (RM); simona.cocco@phys.ens.fr (SC); psulc@asu.edu (PŠ)

  Affiliation Laboratoire de Physique de l’Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, Paris, France

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• Petr Šulc

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: remi.monasson@phys.ens.fr (RM); simona.cocco@phys.ens.fr (SC); psulc@asu.edu (PŠ)

  Affiliation School of Molecular Sciences and Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

  https://orcid.org/0000-0003-1565-6769

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