Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease

• Chirag Gupta,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0002-6121-7065

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• Jielin Xu,

  Roles Formal analysis, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Ting Jin,

  Roles Formal analysis, Software

  Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0001-5073-0667

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• Saniya Khullar,

  Roles Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Xiaoyu Liu,

  Roles Formal analysis

  Affiliation Department of Statistics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Sayali Alatkar,

  Roles Formal analysis

  Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0001-5984-461X

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• Feixiong Cheng,

  Roles Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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• Daifeng Wang

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: daifeng.wang@wisc.edu

  Affiliations Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  https://orcid.org/0000-0001-9190-3704

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