MaxHiC: A robust background correction model to identify biologically relevant chromatin interactions in Hi-C and capture Hi-C experiments

• Hamid Alinejad-Rokny ,

  Contributed equally to this work with: Hamid Alinejad-Rokny, Rassa Ghavami Modegh

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: h.alinejad@ieee.org (HAR); alistair.forrest@gmail.com (ARRF)

  ¶‡ These authors share first authorship on this work.

  Affiliations Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Australia, Bio Medical Machine Learning Lab (BML), The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, Australia, Health Data Analytics Program, AI-enabled Processes (AIP) Research Centre, Macquarie University, Sydney, Australia

  https://orcid.org/0000-0002-2189-9153

  ⨯
• Rassa Ghavami Modegh ,

  Contributed equally to this work with: Hamid Alinejad-Rokny, Rassa Ghavami Modegh

  Roles Data curation, Formal analysis, Methodology, Software, Visualization

  ¶‡ These authors share first authorship on this work.

  Affiliation Bioinformatics and Computational Biology Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran

  https://orcid.org/0000-0002-6872-0130

  ⨯
• Hamid R. Rabiee,

  Roles Investigation, Methodology, Supervision

  Affiliation Bioinformatics and Computational Biology Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran

  https://orcid.org/0000-0002-9835-4493

  ⨯
• Ehsan Ramezani Sarbandi,

  Roles Data curation, Visualization

  Affiliation Bioinformatics and Computational Biology Lab, Department of Computer Engineering, Sharif University of Technology, Tehran, Iran

  ⨯
• Narges Rezaie,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Center for Complex Biological Systems, University of California Irvine, Irvine, California, United States of America

  https://orcid.org/0000-0001-9326-9954

  ⨯
• Kin Tung Tam,

  Roles Resources, Writing – review & editing

  Affiliation Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Australia

  https://orcid.org/0000-0001-9984-6345

  ⨯
• Alistair R. R. Forrest

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: h.alinejad@ieee.org (HAR); alistair.forrest@gmail.com (ARRF)

  Affiliation Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Australia

  https://orcid.org/0000-0003-4543-1675

  ⨯