A new model of Notch signalling: Control of Notch receptor cis-inhibition via Notch ligand dimers

• Daipeng Chen ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  ¶‡ RMHM and DAB contributed equally to this work. DC and ZF authors share first authorship on this work.

  Affiliations School of Mathematics and Statistics, Xi’an Jiaotong University, Xi’an, China, Mathematical Institute, Leiden University, Leiden, The Netherlands

  https://orcid.org/0000-0002-6000-0331

  ⨯
• Zary Forghany ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  ¶‡ RMHM and DAB contributed equally to this work. DC and ZF authors share first authorship on this work.

  Affiliation Leiden University Medical Center (LUMC), Department of Cell & Chemical Biology, Leiden, The Netherlands

  ⨯
• Xinxin Liu ,

  Contributed equally to this work with: Xinxin Liu, Haijiang Wang

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Leiden University Medical Center (LUMC), Department of Cell & Chemical Biology, Leiden, The Netherlands

  https://orcid.org/0000-0003-3722-9020

  ⨯
• Haijiang Wang ,

  Contributed equally to this work with: Xinxin Liu, Haijiang Wang

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Leiden University Medical Center (LUMC), Department of Cell & Chemical Biology, Leiden, The Netherlands, Department of General Surgery, The First Affiliated Hospital, Xi’an Jiaotong University, Xi’an, China

  https://orcid.org/0000-0003-4346-8693

  ⨯
• Roeland M. H. Merks ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: merksrmh@math.leidenuniv.nl (RMHM); d.baker@lumc.nl (DAB)

  ¶‡ RMHM and DAB contributed equally to this work. DC and ZF authors share first authorship on this work.

  Affiliations Mathematical Institute, Leiden University, Leiden, The Netherlands, Institute of Biology Leiden, Leiden University, Leiden, The Netherlands

  https://orcid.org/0000-0002-6152-687X

  ⨯
• David A. Baker

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: merksrmh@math.leidenuniv.nl (RMHM); d.baker@lumc.nl (DAB)

  ¶‡ RMHM and DAB contributed equally to this work. DC and ZF authors share first authorship on this work.

  Affiliation Leiden University Medical Center (LUMC), Department of Cell & Chemical Biology, Leiden, The Netherlands

  https://orcid.org/0000-0001-5533-2828

  ⨯