Mutational analysis of SARS-CoV-2 variants of concern reveals key tradeoffs between receptor affinity and antibody escape

• Emily K. Makowski,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, United States of America, Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-9709-9873

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• John S. Schardt,

  Roles Writing – review & editing

  Affiliations Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, United States of America, Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-5605-4732

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• Matthew D. Smith,

  Roles Formal analysis

  Affiliations Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

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• Peter M. Tessier

  Roles Conceptualization, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: ptessier@umich.edu

  Affiliations Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, United States of America, Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America, Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

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