Spatially resolved in silico modeling of NKG2D signaling kinetics suggests a key role of NKG2D and Vav1 Co-clustering in generating natural killer cell activation

• Rajdeep Kaur Grewal,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Battelle Center for Mathematical Medicine, Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, Ohio, United States of America

  https://orcid.org/0000-0003-0497-3742

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• Jayajit Das

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jayajit@gmail.com

  Affiliations Battelle Center for Mathematical Medicine, Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, Ohio, United States of America, Biomedical Sciences Graduate Program, The Ohio State University, Columbus, Ohio, United States of America, Department of Pediatrics, The Ohio State University, Columbus, Ohio, United States of America, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, Ohio, United States of America, Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America, Biophysics Graduate Program, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0001-9649-4698

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