A genome-scale metabolic model of Cupriavidus necator H16 integrated with TraDIS and transcriptomic data reveals metabolic insights for biotechnological applications

• Nicole Pearcy ,

  Contributed equally to this work with: Nicole Pearcy, Marco Garavaglia

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Nicole.pearcy@nottingham.ac.uk (NP); m.garavaglia@nottingham.ac.uk (MG); jamie.twycross@nottingham.ac.uk (JT); nigel.minton@nottingham.ac.uk (NPM)

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0001-8872-6436

  ⨯
• Marco Garavaglia ,

  Contributed equally to this work with: Nicole Pearcy, Marco Garavaglia

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Nicole.pearcy@nottingham.ac.uk (NP); m.garavaglia@nottingham.ac.uk (MG); jamie.twycross@nottingham.ac.uk (JT); nigel.minton@nottingham.ac.uk (NPM)

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0003-0201-3289

  ⨯
• Thomas Millat,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-5023-4142

  ⨯
• James P. Gilbert,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Current address: Janssen Research & Development, LLC., Observational Health and Data Analytics, Raritan, New Jersey, United States of America

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0003-2294-3459

  ⨯
• Yoseb Song,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

  ⨯
• Hassan Hartman,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Current address: Joint Modelling Team, UK Health Security Agency, London, United Kingdom

  Affiliation School of Biological & Medical Sciences, Oxford Brookes University, Oxford, United Kingdom

  https://orcid.org/0000-0003-0019-1364

  ⨯
• Craig Woods,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Current address: Deep Branch Biotechnology, MTIF Building, Clifton Lane, Nottingham, United Kingdom

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0003-3583-9730

  ⨯
• Claudio Tomi-Andrino,

  Roles Methodology, Writing – review & editing

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-3611-2130

  ⨯
• Rajesh Reddy Bommareddy,

  Roles Investigation, Writing – review & editing

  Current address: The hub for biotechnology in the built environment (HBBE), Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-3071-3453

  ⨯
• Byung-Kwan Cho,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

  https://orcid.org/0000-0003-4788-4184

  ⨯
• David A. Fell,

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation School of Biological & Medical Sciences, Oxford Brookes University, Oxford, United Kingdom

  https://orcid.org/0000-0001-6669-2247

  ⨯
• Mark Poolman,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation School of Biological & Medical Sciences, Oxford Brookes University, Oxford, United Kingdom

  ⨯
• John R. King,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation School of Mathematical Sciences, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-6228-8375

  ⨯
• Klaus Winzer,

  Roles Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  ⨯
• Jamie Twycross ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: Nicole.pearcy@nottingham.ac.uk (NP); m.garavaglia@nottingham.ac.uk (MG); jamie.twycross@nottingham.ac.uk (JT); nigel.minton@nottingham.ac.uk (NPM)

  Affiliation School of Computer Science, University of Nottingham, Nottingham, United Kingdom

  https://orcid.org/0000-0002-1684-0886

  ⨯
•  [ ... ],
• Nigel P. Minton

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: Nicole.pearcy@nottingham.ac.uk (NP); m.garavaglia@nottingham.ac.uk (MG); jamie.twycross@nottingham.ac.uk (JT); nigel.minton@nottingham.ac.uk (NPM)

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

  ⨯
• [ view all ]
• [ view less ]