Predicting the functional impact of KCNQ1 variants with artificial neural networks

• Saksham Phul,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America

  https://orcid.org/0000-0002-2771-2572

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• Georg Kuenze,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America, Institute for Drug Discovery, Leipzig University, Leipzig, Germany

  https://orcid.org/0000-0003-1799-346X

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• Carlos G. Vanoye,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-4935-1122

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• Charles R. Sanders,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America, Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States of America

  https://orcid.org/0000-0003-2046-2862

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• Alfred L. George Jr.,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-3993-966X

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• Jens Meiler

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: jens@meilerlab.org

  Affiliations Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America, Institute for Drug Discovery, Leipzig University, Leipzig, Germany, Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, United States of America

  https://orcid.org/0000-0001-8945-193X

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