Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity

• Szilvia Barsi,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary

  https://orcid.org/0000-0002-8779-2383

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• Henrietta Papp,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations National Laboratory of Virology, University of Pécs, Pécs, Hungary, Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary

  https://orcid.org/0000-0003-3887-5657

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• Alberto Valdeolivas,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany

  https://orcid.org/0000-0001-5482-9023

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• Dániel J. Tóth,

  Roles Investigation, Resources, Validation, Writing – review & editing

  Affiliation Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary

  https://orcid.org/0000-0001-6670-3348

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• Anett Kuczmog,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations National Laboratory of Virology, University of Pécs, Pécs, Hungary, Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary

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• Mónika Madai,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations National Laboratory of Virology, University of Pécs, Pécs, Hungary, Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary

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• László Hunyady,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliations Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary, MTA-SE Laboratory of Molecular Physiology, Budapest, Hungary, Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary

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• Péter Várnai,

  Roles Funding acquisition, Investigation, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary, MTA-SE Laboratory of Molecular Physiology, Budapest, Hungary

  https://orcid.org/0000-0002-7777-806X

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• Julio Saez-Rodriguez,

  Roles Supervision, Writing – review & editing

  Affiliation Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany

  https://orcid.org/0000-0002-8552-8976

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• Ferenc Jakab,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations National Laboratory of Virology, University of Pécs, Pécs, Hungary, Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary

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• Bence Szalai

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ben.szalai@gmail.com

  Current address: Turbine Simulated Cell Technologies Ltd., Budapest, Hungary

  Affiliation Semmelweis University, Faculty of Medicine, Department of Physiology, Budapest, Hungary

  https://orcid.org/0000-0002-9320-5704

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