Novel feature selection methods for construction of accurate epigenetic clocks

Adam Li; Amber Mueller; Brad English; Anthony Arena; Daniel Vera; Alice E. Kane; David A. Sinclair

doi:10.1371/journal.pcbi.1009938

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Open Access

Peer-reviewed

Research Article

Novel feature selection methods for construction of accurate epigenetic clocks

Adam Li,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0001-5075-5194

⨯
Amber Mueller,

Roles Conceptualization, Project administration, Writing – review & editing

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0002-2842-1072

⨯
Brad English,

Roles Conceptualization, Writing – review & editing

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0001-5957-3063

⨯
Anthony Arena,

Roles Software, Writing – review & editing

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Daniel Vera,

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0003-2202-7397

⨯
Alice E. Kane,

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0002-4303-0491

⨯
David A. Sinclair

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: David_Sinclair@hms.harvard.edu

Affiliation Blavatnik Institute, Dept. of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0002-9936-436X

⨯

Novel feature selection methods for construction of accurate epigenetic clocks

Adam Li,
Amber Mueller,
Brad English,
Anthony Arena,
Daniel Vera,
Alice E. Kane,
David A. Sinclair

Published: August 19, 2022
https://doi.org/10.1371/journal.pcbi.1009938

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