IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data

• Tiam Heydari,

  Roles Conceptualization, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliations School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-0465-8312

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• Matthew A. Langley,

  Roles Investigation, Software, Writing – review & editing

  Current address: Division of Biology and Bioengineering, California Institute of Technology, Pasadena, United States of America

  Affiliation Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada

  https://orcid.org/0000-0003-2890-5584

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• Cynthia L. Fisher,

  Roles Investigation, Writing – review & editing

  Affiliations School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-6089-4868

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• Daniel Aguilar-Hidalgo,

  Roles Writing – original draft, Writing – review & editing

  Affiliations School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-1366-9574

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• Shreya Shukla,

  Roles Investigation

  Affiliations Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada, Notch Therapeutics, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-5827-6059

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• Ayako Yachie-Kinoshita,

  Roles Software

  Current address: The Systems Biology Institute, Shinagawa, Tokyo, Japan

  Affiliation Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada

  https://orcid.org/0000-0003-2032-227X

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• Michael Hughes,

  Roles Investigation

  Affiliation Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada

  https://orcid.org/0000-0002-7925-6070

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• Kelly M. McNagny,

  Roles Resources, Writing – review & editing

  Affiliations School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada

  https://orcid.org/0000-0003-4737-3499

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• Peter W. Zandstra

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: peter.zandstra@ubc.ca

  Affiliations School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0002-9568-733X

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