A mechanistic modeling framework reveals the key principles underlying tumor metabolism

• Shubham Tripathi,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations PhD Program in Systems, Synthetic, and Physical Biology, Rice University, Houston, Texas, United States of America, Center for Theoretical Biological Physics and Department of Physics, Northeastern University, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-0141-987X

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• Jun Hyoung Park,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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• Shivanand Pudakalakatti,

  Roles Investigation

  Affiliation Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

  https://orcid.org/0000-0002-6210-2104

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• Pratip K. Bhattacharya,

  Roles Investigation

  Affiliation Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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• Benny Abraham Kaipparettu,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America

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• Herbert Levine

  Roles Conceptualization, Supervision, Writing – review & editing

  * E-mail: h.levine@northeastern.edu

  Affiliation Center for Theoretical Biological Physics and Department of Physics, Northeastern University, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-8819-9055

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