Machine learning-driven identification of drugs inhibiting cytochrome P450 2C9

• Elodie Goldwaser,

  Roles Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation INSERM U1268 « Medicinal Chemistry and Translational Research », UMR 8038 CiTCoM, CNRS—University of Paris, Paris, France

  https://orcid.org/0000-0001-5622-9160

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• Catherine Laurent,

  Roles Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation University of Paris, INSERM U1138, Paris, France

  https://orcid.org/0000-0002-0459-4796

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• Nathalie Lagarde,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Laboratoire GBCM, EA7528, Conservatoire National des Arts et Métiers, 2 Rue Conté, Hésam Université, Paris, France

  https://orcid.org/0000-0002-6048-9800

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• Sylvie Fabrega,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Viral Vector for Gene Transfer core facility, Université de Paris—Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS3633, Paris, France

  https://orcid.org/0000-0002-4145-5488

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• Laure Nay,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Viral Vector for Gene Transfer core facility, Université de Paris—Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS3633, Paris, France

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• Bruno O. Villoutreix,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation INSERM UMR 1141, Robert-Debré Hospital, Paris, France

  https://orcid.org/0000-0002-6456-7730

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• Christian Jelsch,

  Roles Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation CRM2, UMR CNRS 7036, Université de Lorraine, Nancy, France

  https://orcid.org/0000-0002-2655-0313

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• Arnaud B. Nicot,

  Roles Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation INSERM, Nantes Université, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, Nantes, France

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• Marie-Anne Loriot ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: marie-anne.loriot@parisdescartes.fr (MAL); maria.mitev@inserm.fr (MAM)

  Affiliations University of Paris, INSERM U1138, Paris, France, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Biochimie, Paris, France

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• Maria A. Miteva

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: marie-anne.loriot@parisdescartes.fr (MAL); maria.mitev@inserm.fr (MAM)

  Affiliation INSERM U1268 « Medicinal Chemistry and Translational Research », UMR 8038 CiTCoM, CNRS—University of Paris, Paris, France

  https://orcid.org/0000-0001-6895-1214

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