Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis

• Jan Ewald ,

  Contributed equally to this work with: Jan Ewald, Flora Rivieccio

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  * E-mail: jan.ewald@uni-leipzig.de (JE); stefan.schu@uni-jena.de (SS); axel.brakhage@leibniz-hki.de (AAB)

  Affiliations Department of Bioinformatics, Friedrich Schiller University Jena, Jena, Germany, Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), University of Leipzig, Leipzig, Germany

  https://orcid.org/0000-0002-9415-2317

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• Flora Rivieccio ,

  Contributed equally to this work with: Jan Ewald, Flora Rivieccio

  Roles Data curation, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena, Germany, Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University Jena, Jena, Germany

  https://orcid.org/0000-0002-1009-5328

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• Lukáš Radosa,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena, Germany

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• Stefan Schuster ,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: jan.ewald@uni-leipzig.de (JE); stefan.schu@uni-jena.de (SS); axel.brakhage@leibniz-hki.de (AAB)

  Affiliation Department of Bioinformatics, Friedrich Schiller University Jena, Jena, Germany

  https://orcid.org/0000-0003-0470-9802

  ⨯
• Axel A. Brakhage ,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: jan.ewald@uni-leipzig.de (JE); stefan.schu@uni-jena.de (SS); axel.brakhage@leibniz-hki.de (AAB)

  ¶‡ AAB and CK also contributed equally to this work.

  Affiliations Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena, Germany, Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University Jena, Jena, Germany

  https://orcid.org/0000-0002-8814-4193

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• Christoph Kaleta

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ AAB and CK also contributed equally to this work.

  Affiliation Research Group Medical Systems Biology, Institute of Experimental Medicine, Kiel University, Kiel, Germany

  https://orcid.org/0000-0001-8004-9514

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