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Open Access
Peer-reviewed
Research Article
A systems genomics approach uncovers molecular associates of RSV severity
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Matthew N. McCall,
Roles Conceptualization, Formal analysis, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester New York, United States of America, Department of Biomedical Genetics, University of Rochester Medical Center, Rochester New York, United States of America
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Chin-Yi Chu ,
Contributed equally to this work with: Chin-Yi Chu, Lu Wang
Roles Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Division of Neonatology and Pediatric Molecular and Personalized Medicine Program, University of Rochester Medical Center, Rochester New York, United States of America, Department of Pediatrics, University of Rochester Medical Center, Rochester New York, United States of America
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Lu Wang ,
Contributed equally to this work with: Chin-Yi Chu, Lu Wang
Roles Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester New York, United States of America
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Lauren Benoodt,
Roles Formal analysis, Methodology, Software, Validation, Visualization
Affiliation Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester New York, United States of America
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Juilee Thakar,
Roles Formal analysis, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester New York, United States of America, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester New York, United States of America
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Anthony Corbett,
Roles Data curation
Affiliations Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester New York, United States of America, Clinical and Translational Science Institute, University of Rochester Medical Center, Rochester New York, United States of America
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Jeanne Holden-Wiltse,
Roles Data curation
Affiliations Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester New York, United States of America, Clinical and Translational Science Institute, University of Rochester Medical Center, Rochester New York, United States of America
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Christopher Slaunwhite,
Roles Formal analysis
Affiliations Division of Neonatology and Pediatric Molecular and Personalized Medicine Program, University of Rochester Medical Center, Rochester New York, United States of America, Department of Pediatrics, University of Rochester Medical Center, Rochester New York, United States of America
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Alex Grier,
Roles Formal analysis
Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester New York, United States of America
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Steven R. Gill,
Roles Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester New York, United States of America
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Ann R. Falsey,
Roles Funding acquisition, Resources
Affiliations Department of Medicine, University of Rochester Medical Center, Rochester New York, United States of America, Department of Medicine, Rochester General Hospital, Rochester New York, United States of America
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David J. Topham,
Roles Funding acquisition, Resources
Affiliations Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester New York, United States of America, David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester New York, United States of America
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Mary T. Caserta,
Roles Conceptualization, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
Affiliation Department of Pediatrics, University of Rochester Medical Center, Rochester New York, United States of America
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Edward E. Walsh,
Roles Conceptualization, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Medicine, University of Rochester Medical Center, Rochester New York, United States of America, Department of Medicine, Rochester General Hospital, Rochester New York, United States of America
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Xing Qiu ,
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: xing_qiu@urmc.rochester.edu (XQ); Tom_Mariani@urmc.rochester.edu (TJM)
Affiliation Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester New York, United States of America
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Thomas J. Mariani
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: xing_qiu@urmc.rochester.edu (XQ); Tom_Mariani@urmc.rochester.edu (TJM)
Affiliations Division of Neonatology and Pediatric Molecular and Personalized Medicine Program, University of Rochester Medical Center, Rochester New York, United States of America, Department of Pediatrics, University of Rochester Medical Center, Rochester New York, United States of America
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A systems genomics approach uncovers molecular associates of RSV severity
- Matthew N. McCall,
- Chin-Yi Chu,
- Lu Wang,
- Lauren Benoodt,
- Juilee Thakar,
- Anthony Corbett,
- Jeanne Holden-Wiltse,
- Christopher Slaunwhite,
- Alex Grier,
- Steven R. Gill
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- Published: December 28, 2021
- https://doi.org/10.1371/journal.pcbi.1009617