Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones

• Erik B. Nordquist,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America

  https://orcid.org/0000-0001-9139-0152

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• Charles A. English,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America, Impact, New York City, New York, United States of America

  https://orcid.org/0000-0001-7306-9883

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• Eugenia M. Clerico,

  Roles Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America

  https://orcid.org/0000-0002-4433-8842

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• Woody Sherman,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America, Roivant Sciences, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-9079-1376

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• Lila M. Gierasch ,

  Roles Conceptualization, Writing – review & editing

  * E-mail: gierasch@biochem.umass.edu (LMG); jianhanc@umass.edu (JC)

  Affiliations Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America, Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America

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• Jianhan Chen

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: gierasch@biochem.umass.edu (LMG); jianhanc@umass.edu (JC)

  Affiliations Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America, Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America

  https://orcid.org/0000-0002-5281-1150

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