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Open Access
Peer-reviewed
Research Article
TwinCons: Conservation score for uncovering deep sequence similarity and divergence
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Petar I. Penev,
Roles Conceptualization, Formal analysis, Methodology, Software, Validation, Writing – original draft, Writing – review & editing
Affiliations NASA Center for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, United States of America, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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Claudia Alvarez-Carreño,
Roles Formal analysis, Methodology, Validation
Affiliations NASA Center for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, United States of America, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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Eric Smith,
Roles Methodology, Writing – review & editing
Affiliations NASA Center for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, United States of America, Earth-Life Science Institute, Tokyo Institute of Technology, Meguro-ku, Tokyo, Japan, Santa Fe Institute, Santa Fe, New Mexico, United States of America, Department of Physics, The University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Ronin Institute, Montclair, New Jersey, United States of America
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Anton S. Petrov ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: anton.petrov@biology.gatech.edu (ASP); loren.williams@chemistry.gatech.edu (LDW)
Affiliations NASA Center for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, United States of America, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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Loren Dean Williams
Roles Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: anton.petrov@biology.gatech.edu (ASP); loren.williams@chemistry.gatech.edu (LDW)
Affiliations NASA Center for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, United States of America, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, United States of America
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TwinCons: Conservation score for uncovering deep sequence similarity and divergence
- Petar I. Penev,
- Claudia Alvarez-Carreño,
- Eric Smith,
- Anton S. Petrov,
- Loren Dean Williams
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- Published: October 29, 2021
- https://doi.org/10.1371/journal.pcbi.1009541