Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy

• Alexander B. Brummer ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: abrummer@coh.org (ABB); cbrown@coh.org (CEB); rrockne@coh.org (RCR)

  Affiliation Department of Computational and Quantitative Medicine, Division of Mathematical Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

  https://orcid.org/0000-0002-8776-0939

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• Xin Yang ,

  Roles Data curation, Investigation, Methodology, Validation

  ¶† Deceased.

  Affiliation Department of Hematology and Hematopoietic Cell Translation and Immuno-Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

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• Eric Ma,

  Roles Data curation, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Hematology and Hematopoietic Cell Translation and Immuno-Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

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• Margarita Gutova,

  Roles Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Department of Stem Cell Biology and Regenerative Medicine, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

  https://orcid.org/0000-0002-7094-626X

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• Christine E. Brown ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: abrummer@coh.org (ABB); cbrown@coh.org (CEB); rrockne@coh.org (RCR)

  Affiliation Department of Hematology and Hematopoietic Cell Translation and Immuno-Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

  https://orcid.org/0000-0003-4915-8207

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• Russell C. Rockne

  Roles Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: abrummer@coh.org (ABB); cbrown@coh.org (CEB); rrockne@coh.org (RCR)

  Affiliation Department of Computational and Quantitative Medicine, Division of Mathematical Oncology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

  https://orcid.org/0000-0002-1557-159X

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