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The meaning of significant mean group differences for biomarker discovery
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Eva Loth,
Affiliations Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, Sackler Institute for Translational Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Jumana Ahmad,
Affiliation Department of Psychology, Social Work and Counselling, Faculty of Education and Health, University of Greenwich, London, United Kingdom
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Chris Chatham,
Affiliation Neuroscience & Rare Diseases, Pharma Research & Early Development, Roche Innovation Center New York, New York, United States of America
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Beatriz López,
Affiliation Department of Psychology, Portsmouth University, Portsmouth, United Kingdom
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Ben Carter,
Affiliation Department of Biostatistics, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Daisy Crawley,
Affiliation Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Bethany Oakley,
Affiliation Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Hannah Hayward,
Affiliation Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Jennifer Cooke,
Affiliation Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Antonia San José Cáceres,
Affiliations Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, Instituto de Investigación Sanitaria Gregorio Marañón, Departamento de Psiquiatría del Niño y del Adolescente, Hospital General Universitario Gregorio Marañón and Centro Investigación Biomédica en Red Salud Mental (CIBERSAM), Madrid, Spain
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Danilo Bzdok,
Affiliations Department of Biomedical Engineering, McConnell Brain-Imaging Centre (BIC), Montreal Neurological Institute (MNI), Faculty of Medicine, McGill University, Montreal, Canada, Canadian Institute for Advanced Research (CIFAR), Canada, Mila–Quebec Artificial Intelligence Institute, Montreal, Canada
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Emily Jones,
Affiliation Centre for Brain and Cognitive Development, Birkbeck, University of London, London, United Kingdom
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Tony Charman,
Affiliation Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Christian Beckmann,
Affiliation Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, the Netherlands
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Thomas Bourgeron,
Affiliation Human Genetics and Cognitive Functions, Institut Pasteur, UMR3571 CNRS, Université de Paris, Paris, France
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Roberto Toro,
Affiliation Human Genetics and Cognitive Functions, Institut Pasteur, UMR3571 CNRS, Université de Paris, Paris, France
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Jan Buitelaar,
Affiliation Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, the Netherlands
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Declan Murphy,
Affiliations Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom, Sackler Institute for Translational Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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Guillaume Dumas
* E-mail: guillaume.dumas@umontreal.ca
Affiliations Mila–Quebec Artificial Intelligence Institute, Montreal, Canada, Human Genetics and Cognitive Functions, Institut Pasteur, UMR3571 CNRS, Université de Paris, Paris, France, Precision Psychiatry and Social Physiology laboratory, CHU Sainte-Justine Research Center, Department of Psychiatry, University of Montreal, Quebec, Canada
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The meaning of significant mean group differences for biomarker discovery
- Eva Loth,
- Jumana Ahmad,
- Chris Chatham,
- Beatriz López,
- Ben Carter,
- Daisy Crawley,
- Bethany Oakley,
- Hannah Hayward,
- Jennifer Cooke,
- Antonia San José Cáceres
- Published: November 18, 2021
- https://doi.org/10.1371/journal.pcbi.1009477