Analysis of 11,430 recombinant protein production experiments reveals that protein yield is tunable by synonymous codon changes of translation initiation sites

• Bikash K. Bhandari ,

  Contributed equally to this work with: Bikash K. Bhandari, Chun Shen Lim

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

  https://orcid.org/0000-0001-8698-5258

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• Chun Shen Lim ,

  Contributed equally to this work with: Bikash K. Bhandari, Chun Shen Lim

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

  https://orcid.org/0000-0001-7015-0125

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• Daniela M. Remus,

  Roles Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Callaghan Innovation Protein Science and Engineering, University of Canterbury, Christchurch, New Zealand

  https://orcid.org/0000-0002-6596-7197

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• Augustine Chen,

  Roles Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

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• Craig van Dolleweerd,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Biomolecular Interaction Center, University of Canterbury, Christchurch, New Zealand

  https://orcid.org/0000-0002-1380-6930

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• Paul P. Gardner

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: paul.gardner@otago.ac.nz

  Affiliations Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand, Biomolecular Interaction Center, University of Canterbury, Christchurch, New Zealand

  https://orcid.org/0000-0002-7808-1213

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