Deep geometric representations for modeling effects of mutations on protein-protein binding affinity

• Xianggen Liu,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Laboratory for Brain and Intelligence and Department of Biomedical Engineering, Tsinghua University, Beijing, China, School of Computing and Artificial Intelligence, Southwest Jiaotong University, Chengdu, China, Beijing Innovation Center for Future Chip, Tsinghua University, Beijing, China

  https://orcid.org/0000-0001-6368-2043

  ⨯
• Yunan Luo,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

  https://orcid.org/0000-0001-7728-6412

  ⨯
• Pengyong Li,

  Roles Methodology, Validation

  Affiliations Laboratory for Brain and Intelligence and Department of Biomedical Engineering, Tsinghua University, Beijing, China, Beijing Innovation Center for Future Chip, Tsinghua University, Beijing, China

  https://orcid.org/0000-0001-5971-046X

  ⨯
• Sen Song ,

  Roles Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: jianpeng@illinois.edu (JP); songsen@tsinghua.edu.cn (SS)

  Affiliations Laboratory for Brain and Intelligence and Department of Biomedical Engineering, Tsinghua University, Beijing, China, Beijing Innovation Center for Future Chip, Tsinghua University, Beijing, China

  ⨯
• Jian Peng

  Roles Conceptualization, Methodology, Writing – review & editing

  * E-mail: jianpeng@illinois.edu (JP); songsen@tsinghua.edu.cn (SS)

  Affiliation Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

  https://orcid.org/0000-0002-1736-2978

  ⨯