Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations

Pedro de Atauri; Míriam Tarrado-Castellarnau; Josep Tarragó-Celada; Carles Foguet; Effrosyni Karakitsou; Josep Joan Centelles; Marta Cascante

doi:10.1371/journal.pcbi.1009234

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Peer-reviewed

Research Article

Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations

Pedro de Atauri ,

Contributed equally to this work with: Pedro de Atauri, Míriam Tarrado-Castellarnau

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: pde_atauri@ub.edu (PdA); martacascante@ub.edu (MC)

Affiliations Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) and Metabolomics node at Spanish National Bioinformatics Institute (INB-ISCIII-ES-ELIXIR), Instituto de Salud Carlos III (ISCIII), Madrid, Spain
⨯
Míriam Tarrado-Castellarnau ,

Contributed equally to this work with: Pedro de Atauri, Míriam Tarrado-Castellarnau

Roles Data curation, Formal analysis, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) and Metabolomics node at Spanish National Bioinformatics Institute (INB-ISCIII-ES-ELIXIR), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

https://orcid.org/0000-0001-9757-2686

⨯
Josep Tarragó-Celada,

Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

Affiliation Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain

https://orcid.org/0000-0001-7322-9736

⨯
Carles Foguet,

Roles Methodology, Writing – review & editing

Affiliations Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) and Metabolomics node at Spanish National Bioinformatics Institute (INB-ISCIII-ES-ELIXIR), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

https://orcid.org/0000-0001-8494-9595

⨯
Effrosyni Karakitsou,

Roles Methodology, Writing – review & editing

Affiliation Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain

https://orcid.org/0000-0002-3206-7010

⨯
Josep Joan Centelles,

Roles Formal analysis, Project administration, Resources, Supervision, Writing – review & editing

Affiliations Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) and Metabolomics node at Spanish National Bioinformatics Institute (INB-ISCIII-ES-ELIXIR), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

https://orcid.org/0000-0002-6289-9678

⨯
Marta Cascante

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: pde_atauri@ub.edu (PdA); martacascante@ub.edu (MC)

Affiliations Department of Biochemistry and Molecular Biomedicine & Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) and Metabolomics node at Spanish National Bioinformatics Institute (INB-ISCIII-ES-ELIXIR), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

https://orcid.org/0000-0002-2062-4633

⨯

Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations

Pedro de Atauri,
Míriam Tarrado-Castellarnau,
Josep Tarragó-Celada,
Carles Foguet,
Effrosyni Karakitsou,
Josep Joan Centelles,
Marta Cascante

Published: July 23, 2021
https://doi.org/10.1371/journal.pcbi.1009234

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