Single-cell analysis reveals the pan-cancer invasiveness-associated transition of adipose-derived stromal cells into COL11A1-expressing cancer-associated fibroblasts

• Kaiyi Zhu ,

  Contributed equally to this work with: Kaiyi Zhu, Lingyi Cai

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Department of Electrical Engineering, Columbia University, New York, New York, United States of America, Center for Cancer Systems Therapeutics, Columbia University, New York, New York, United States of America

  https://orcid.org/0000-0002-0111-0848

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• Lingyi Cai ,

  Contributed equally to this work with: Kaiyi Zhu, Lingyi Cai

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Department of Electrical Engineering, Columbia University, New York, New York, United States of America, Center for Cancer Systems Therapeutics, Columbia University, New York, New York, United States of America

  https://orcid.org/0000-0002-9193-0806

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• Chenqian Cui,

  Roles Data curation, Formal analysis, Investigation, Software, Writing – review & editing

  Affiliation Department of Electrical Engineering, Columbia University, New York, New York, United States of America

  https://orcid.org/0000-0002-5432-9413

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• Juan R. de los Toyos,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Immunology Department, School of Medicine and Health Sciences, University of Oviedo, Oviedo, Spain

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• Dimitris Anastassiou

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: d.anastassiou@columbia.edu

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Department of Electrical Engineering, Columbia University, New York, New York, United States of America, Center for Cancer Systems Therapeutics, Columbia University, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, United States of America

  https://orcid.org/0000-0003-2459-909X

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