Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis

• Cecilia Wieder,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0003-1548-4346

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• Clément Frainay,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France

  https://orcid.org/0000-0003-4313-2786

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• Nathalie Poupin,

  Roles Writing – review & editing

  Affiliation Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France

  https://orcid.org/0000-0002-3393-1405

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• Pablo Rodríguez-Mier,

  Roles Validation, Writing – review & editing

  Affiliation Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France

  https://orcid.org/0000-0002-4938-4418

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• Florence Vinson,

  Roles Data curation

  Affiliation Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France

  https://orcid.org/0000-0001-8143-8183

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• Juliette Cooke,

  Roles Validation, Writing – review & editing

  Affiliation Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France

  https://orcid.org/0000-0003-2085-0339

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• Rachel PJ Lai,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0003-3418-850X

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• Jacob G. Bundy,

  Roles Conceptualization, Writing – review & editing

  Affiliation Section of Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0002-1164-8465

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• Fabien Jourdan,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France, MetaToul-MetaboHUB, National Infrastructure of Metabolomics and Fluxomics, Toulouse, France

  https://orcid.org/0000-0001-9401-2894

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• Timothy Ebbels

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  * E-mail: t.ebbels@imperial.ac.uk

  Affiliation Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom

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