Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure

• Saskia Haupt ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: saskia.haupt@uni-heidelberg.de

  Affiliations Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany, Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany

  https://orcid.org/0000-0001-7537-9439

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• Alexander Zeilmann,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Image and Pattern Analysis Group (IPA), Heidelberg University, Heidelberg, Germany

  https://orcid.org/0000-0002-8119-0349

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• Aysel Ahadova,

  Roles Resources, Writing – original draft, Writing – review & editing

  Affiliation Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

  https://orcid.org/0000-0001-9890-0450

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• Hendrik Bläker,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Pathology, University Hospital Leipzig, Leipzig, Germany

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• Magnus von Knebel Doeberitz,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

  https://orcid.org/0000-0002-0498-6781

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• Matthias Kloor,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Applied Tumor Biology (ATB), Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

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• Vincent Heuveline

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Engineering Mathematics and Computing Lab (EMCL), Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany, Data Mining and Uncertainty Quantification (DMQ), Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany

  https://orcid.org/0000-0002-2217-7558

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