Multicellular spatial model of RNA virus replication and interferon responses reveals factors controlling plaque growth dynamics

• Josua O. Aponte-Serrano ,

  Contributed equally to this work with: Josua O. Aponte-Serrano, Jordan J. A. Weaver

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America

  https://orcid.org/0000-0001-5959-6302

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• Jordan J. A. Weaver ,

  Contributed equally to this work with: Josua O. Aponte-Serrano, Jordan J. A. Weaver

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemical & Petroleum Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0002-2606-4147

  ⨯
• T. J. Sego,

  Roles Formal analysis, Investigation, Methodology, Resources, Software

  Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America

  https://orcid.org/0000-0002-4274-656X

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• James A. Glazier ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ JAE and JES also contributed equally to this work.

  Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America

  https://orcid.org/0000-0003-3634-190X

  ⨯
• Jason E. Shoemaker

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jason.shoemaker@pitt.edu

  ¶‡ JAE and JES also contributed equally to this work.

  Affiliations Department of Chemical & Petroleum Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0003-3315-7103

  ⨯