Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death

• Irina Veith ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  ¶‡ IV and AM share equal first author contribution. MCP and EM share equal last author contribution

  Affiliations Institut Roche, 4 cours de l’Ile Seguin, Boulogne-Billancourt, France, Institut Curie, INSERM U830, Stress and Cancer Laboratory, PSL Research University, Paris, France

  https://orcid.org/0000-0002-4654-2265

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• Arianna Mencattini ,

  Roles Conceptualization, Formal analysis, Investigation, Software, Writing – original draft, Writing – review & editing

  ¶‡ IV and AM share equal first author contribution. MCP and EM share equal last author contribution

  Affiliation Department of Electronic Engineering, University of Rome Tor Vergata, Rome, Italy

  https://orcid.org/0000-0002-3753-0457

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• Valentin Picant,

  Roles Investigation, Writing – review & editing

  Affiliation Institut Curie, INSERM U830, Stress and Cancer Laboratory, PSL Research University, Paris, France

  https://orcid.org/0000-0001-9514-0492

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• Marco Serra,

  Roles Methodology, Writing – review & editing

  Affiliation Institut Curie, CNRS UMR168, Laboratoire Physico Chimie Curie, Institut Pierre-Gilles de Gennes, PSL Research University, Paris, France

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• Marine Leclerc,

  Roles Resources, Writing – review & editing

  Affiliation INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Fac. de Médecine—Univ. Paris-Sud, Université Paris-Saclay, Villejuif, France

  https://orcid.org/0000-0003-2165-5244

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• Maria Colomba Comes,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Electronic Engineering, University of Rome Tor Vergata, Rome, Italy

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• Fathia Mami-Chouaib,

  Roles Resources, Writing – review & editing

  Affiliation INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Fac. de Médecine—Univ. Paris-Sud, Université Paris-Saclay, Villejuif, France

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• Jacques Camonis,

  Roles Conceptualization, Writing – review & editing

  Affiliation Institut Curie, INSERM U830, Stress and Cancer Laboratory, PSL Research University, Paris, France

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• Stéphanie Descroix,

  Roles Methodology, Writing – review & editing

  Affiliation Institut Curie, CNRS UMR168, Laboratoire Physico Chimie Curie, Institut Pierre-Gilles de Gennes, PSL Research University, Paris, France

  https://orcid.org/0000-0003-0027-352X

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• Hamasseh Shirvani,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Institut Roche, 4 cours de l’Ile Seguin, Boulogne-Billancourt, France

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• Fatima Mechta-Grigoriou,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Institut Curie, INSERM U830, Stress and Cancer Laboratory, PSL Research University, Paris, France

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• Gérard Zalcman,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations Institut Curie, INSERM U830, Stress and Cancer Laboratory, PSL Research University, Paris, France, CIC INSERM 1425, Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, Université de Paris, Paris, France

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• Maria Carla Parrini ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: martinelli@ing.uniroma2.it (EM); maria-carla.parrini@curie.fr (MCP)

  ¶‡ IV and AM share equal first author contribution. MCP and EM share equal last author contribution

  Affiliation Institut Curie, INSERM U830, Stress and Cancer Laboratory, PSL Research University, Paris, France

  https://orcid.org/0000-0002-7082-9792

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• Eugenio Martinelli

  Roles Conceptualization, Funding acquisition, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: martinelli@ing.uniroma2.it (EM); maria-carla.parrini@curie.fr (MCP)

  ¶‡ IV and AM share equal first author contribution. MCP and EM share equal last author contribution

  Affiliation Department of Electronic Engineering, University of Rome Tor Vergata, Rome, Italy

  https://orcid.org/0000-0002-6673-2066

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