A network-informed analysis of SARS-CoV-2 and hemophagocytic lymphohistiocytosis genes’ interactions points to Neutrophil extracellular traps as mediators of thrombosis in COVID-19

• Jun Ding,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Computational Biology Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America, The Meakins-Christie Laboratories at the Research Institute of the McGill University Heath Centre Research Institute, Montréal, Canada

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• David Earl Hostallero,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Electrical and Computer Engineering, McGill University, Montréal, Canada

  https://orcid.org/0000-0002-1611-8332

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• Mohamed Reda El Khili,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Electrical and Computer Engineering, McGill University, Montréal, Canada

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• Gregory Joseph Fonseca,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation The Meakins-Christie Laboratories at the Research Institute of the McGill University Heath Centre Research Institute, Montréal, Canada

  https://orcid.org/0000-0002-3073-5724

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• Simon Milette,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliation Goodman Cancer Research Centre, McGill University, Montréal, Canada

  https://orcid.org/0000-0003-2977-0829

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• Nuzha Noorah,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation The Meakins-Christie Laboratories at the Research Institute of the McGill University Heath Centre Research Institute, Montréal, Canada

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• Myriam Guay-Belzile,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation The Meakins-Christie Laboratories at the Research Institute of the McGill University Heath Centre Research Institute, Montréal, Canada

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• Jonathan Spicer,

  Roles Conceptualization, Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation Division of Thoracic and Upper Gastrointestinal Surgery, McGill University Health Centre Research Institute, Montréal, Canada

  https://orcid.org/0000-0003-2708-1309

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• Noriko Daneshtalab,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation School of Pharmacy, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada

  https://orcid.org/0000-0002-6715-1263

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• Martin Sirois,

  Roles Conceptualization, Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation Montreal Heart Institute and Department of pharmacology and physiology, Faculty of medicine, Université de Montréal, Montréal, Canada

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• Karine Tremblay,

  Roles Conceptualization, Formal analysis, Visualization, Writing – review & editing

  Affiliation Pharmacology-physiology Department, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-Saint-Jean (Chicoutimi University Hospital) Research Center, Saguenay, Canada

  https://orcid.org/0000-0002-2774-9738

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• Amin Emad ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: amin.emad@mcgill.ca (AE); simon.rousseau@mcgill.ca (SR)

  Affiliation Department of Electrical and Computer Engineering, McGill University, Montréal, Canada

  https://orcid.org/0000-0002-5108-4887

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• Simon Rousseau

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: amin.emad@mcgill.ca (AE); simon.rousseau@mcgill.ca (SR)

  Affiliation The Meakins-Christie Laboratories at the Research Institute of the McGill University Heath Centre Research Institute, Montréal, Canada

  https://orcid.org/0000-0002-8773-575X

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