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Open Access
Peer-reviewed
Research Article
A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways
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Martín Garrido-Rodriguez,
Roles Methodology, Software, Writing – original draft
Affiliations Clinical Bioinformatics Area, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, Sevilla, Spain, Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Córdoba, Spain, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain, Hospital Universitario Reina Sofía, Córdoba, Spain
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Daniel Lopez-Lopez,
Roles Software
Affiliations Clinical Bioinformatics Area, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, Sevilla, Spain, Computational Systems Medicine, Institute of Biomedicine of Seville (IBIS), Sevilla, Spain
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Francisco M. Ortuno,
Roles Methodology, Software
Affiliations Clinical Bioinformatics Area, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, Sevilla, Spain, Computational Systems Medicine, Institute of Biomedicine of Seville (IBIS), Sevilla, Spain
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María Peña-Chilet,
Roles Conceptualization, Methodology
Affiliations Clinical Bioinformatics Area, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, Sevilla, Spain, Computational Systems Medicine, Institute of Biomedicine of Seville (IBIS), Sevilla, Spain, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), FPS, Hospital Virgen del Rocío, Sevilla, Spain
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Eduardo Muñoz,
Roles Conceptualization
Affiliations Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Córdoba, Spain, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain, Hospital Universitario Reina Sofía, Córdoba, Spain
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Marco A. Calzado,
Roles Conceptualization, Supervision
Affiliations Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Córdoba, Spain, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain, Hospital Universitario Reina Sofía, Córdoba, Spain
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Joaquin Dopazo
Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing
* E-mail: joaquin.dopazo@juntadeandalucia.es
Affiliations Clinical Bioinformatics Area, Fundación Progreso y Salud (FPS), Hospital Virgen del Rocío, Sevilla, Spain, Computational Systems Medicine, Institute of Biomedicine of Seville (IBIS), Sevilla, Spain, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), FPS, Hospital Virgen del Rocío, Sevilla, Spain, FPS/ELIXIR-es, Hospital Virgen del Rocío, Sevilla, Spain
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A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways
- Martín Garrido-Rodriguez,
- Daniel Lopez-Lopez,
- Francisco M. Ortuno,
- María Peña-Chilet,
- Eduardo Muñoz,
- Marco A. Calzado,
- Joaquin Dopazo
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- Published: February 11, 2021
- https://doi.org/10.1371/journal.pcbi.1008748