Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies

• David J. Wooten ,

  Contributed equally to this work with: David J. Wooten, Jorge Gómez Tejeda Zañudo

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Physics, Pennsylvania State University, University Park, Pennsylvania, United States of America

  https://orcid.org/0000-0002-0067-123X

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• Jorge Gómez Tejeda Zañudo ,

  Contributed equally to this work with: David J. Wooten, Jorge Gómez Tejeda Zañudo

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliations Eli and Edythe L. Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-1092-0068

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• David Murrugarra,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Mathematics, University of Kentucky, Lexington, Kentucky, United States of America

  https://orcid.org/0000-0001-9710-5025

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• Austin M. Perry,

  Roles Investigation, Methodology, Validation, Writing – original draft

  Affiliations Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, United States of America, Quantitative and Systems Biology Graduate Program, University of California Merced, Merced, California, United States of America

  https://orcid.org/0000-0002-0847-787X

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• Anna Dongari-Bagtzoglou,

  Roles Funding acquisition, Methodology, Writing – original draft

  Affiliation Department of Oral Health and Diagnostic Sciences, University of Connecticut Health Center, Farmington, Connecticut, United States of America

  https://orcid.org/0000-0002-7615-1417

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• Reinhard Laubenbacher,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – original draft

  Affiliation Department of Medicine, University of Florida, Gainesville, Florida, United States of America

  https://orcid.org/0000-0002-9143-9451

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• Clarissa J. Nobile,

  Roles Funding acquisition, Methodology, Supervision, Writing – original draft

  Affiliations Department of Molecular and Cell Biology, School of Natural Sciences, University of California Merced, Merced, California, United States of America, Health Sciences Research Institute, University of California Merced, Merced, California, United States of America

  https://orcid.org/0000-0003-0799-6499

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• Réka Albert

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft

  * E-mail: rza1@psu.edu

  Affiliation Department of Physics, Pennsylvania State University, University Park, Pennsylvania, United States of America

  https://orcid.org/0000-0002-9485-0828

  ⨯