Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning

• Philipp Mergenthaler ,

  Contributed equally to this work with: Philipp Mergenthaler, Santosh Hariharan

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: philipp.mergenthaler@charite.de (PM); david.andrews@sri.utoronto.ca (DWA)

  Affiliations Biological Sciences, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada, Charité — Universitätsmedizin Berlin, Department of Experimental Neurology, Department of Neurology, Center for Stroke Research Berlin, NeuroCure Clinical Research Center, Berlin, Germany, Berlin Institute of Health (BIH), Berlin, Germany

  https://orcid.org/0000-0002-9753-6711

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• Santosh Hariharan ,

  Contributed equally to this work with: Philipp Mergenthaler, Santosh Hariharan

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Biological Sciences, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0002-0941-0044

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• James M. Pemberton,

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Biological Sciences, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-8386-1081

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• Corey Lourenco,

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-9075-7661

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• Linda Z. Penn,

  Roles Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0001-8133-5459

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• David W. Andrews

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: philipp.mergenthaler@charite.de (PM); david.andrews@sri.utoronto.ca (DWA)

  Affiliations Biological Sciences, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

  https://orcid.org/0000-0002-9266-7157

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