miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

• Shay Ben-Elazar ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: shay.benel@gmail.com (SBE); Miriam.Ragle.Aure@rr-research.no (MRA); zohar.yakhini@gmail.com (ZY)

  Affiliations School of Computer Science, Tel-Aviv University, Tel-Aviv, Israel, Department of Computer Science, Interdisciplinary Center, Herzliya, Israel

  https://orcid.org/0000-0002-1461-9168

  ⨯
• Miriam Ragle Aure ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  * E-mail: shay.benel@gmail.com (SBE); Miriam.Ragle.Aure@rr-research.no (MRA); zohar.yakhini@gmail.com (ZY)

  Affiliations Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Department of Medical Genetics, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway

  https://orcid.org/0000-0001-7739-4982

  ⨯
• Kristin Jonsdottir,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Department of Pathology, Stavanger University Hospital, Stavanger, Norway, Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway

  https://orcid.org/0000-0001-9772-925X

  ⨯
• Suvi-Katri Leivonen,

  Roles Conceptualization, Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Helsinki University Hospital Comprehensive Cancer Centre and University of Helsinki, Helsinki, Finland

  https://orcid.org/0000-0003-3224-0757

  ⨯
• Vessela N. Kristensen,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Department of Medical Genetics, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, Department of Clinical Molecular Biology and Laboratory Science (EpiGen), Division of Medicine, Akershus University Hospital, Lørenskog, Norway

  https://orcid.org/0000-0001-5012-7438

  ⨯
• Emiel A. M. Janssen,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Pathology, Stavanger University Hospital, Stavanger, Norway, Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway

  https://orcid.org/0000-0002-7760-5396

  ⨯
• Kristine Kleivi Sahlberg,

  Roles Data curation, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Department of Research, Vestre Viken Hospital Trust, Drammen, Norway

  ⨯
• Ole Christian Lingjærde,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway

  ⨯
• Zohar Yakhini

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: shay.benel@gmail.com (SBE); Miriam.Ragle.Aure@rr-research.no (MRA); zohar.yakhini@gmail.com (ZY)

  Affiliations Department of Computer Science, Interdisciplinary Center, Herzliya, Israel, Department of Computer Science, Technion–Israel Institute of Technology, Haifa, Israel

  https://orcid.org/0000-0002-0420-5412

  ⨯