A multiscale model via single-cell transcriptomics reveals robust patterning mechanisms during early mammalian embryo development

• Zixuan Cang ,

  Contributed equally to this work with: Zixuan Cang, Yangyang Wang

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Mathematics, The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, California, United States of America

  https://orcid.org/0000-0002-9951-5586

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• Yangyang Wang ,

  Contributed equally to this work with: Zixuan Cang, Yangyang Wang

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Mathematics, The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, California, United States of America

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• Qixuan Wang,

  Roles Formal analysis, Validation, Writing – review & editing

  Affiliation Department of Mathematics, University of California, Riverside, Riverside, California, United States of America

  https://orcid.org/0000-0003-2673-921X

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• Ken W. Y. Cho,

  Roles Validation, Writing – review & editing

  Affiliation Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California, United States of America

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• William Holmes,

  Roles Formal analysis, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Physics and Astronomy, Department of Mathematics, Quantitative Systems Biology Center, Vanderbilt University, Nashville, Tennessee, United States of America

  https://orcid.org/0000-0001-6683-4647

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• Qing Nie

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: qnie@math.uci.edu

  Affiliations Department of Mathematics, The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, California, United States of America, Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California, United States of America

  https://orcid.org/0000-0002-8804-3368

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