A novel stochastic simulation approach enables exploration of mechanisms for regulating polarity site movement

• Samuel A. Ramirez ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: s_a_ramirez@outlook.com (SAR); timothy_elston@med.unc.edu (TCE)

  Affiliation Department of Pharmacology and Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0003-0293-2330

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• Michael Pablo,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Current address: Gladstone/University of California San Francisco Center for Cell Circuitry, Gladstone Institutes, San Francisco, California, United States of America

  Affiliations Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Program in Molecular and Cellular Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0001-9738-8109

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• Sean Burk,

  Roles Investigation, Methodology

  Affiliation Department of Pharmacology and Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0001-6012-9322

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• Daniel J. Lew,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina, United States of America

  https://orcid.org/0000-0001-7482-3585

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• Timothy C. Elston

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  * E-mail: s_a_ramirez@outlook.com (SAR); timothy_elston@med.unc.edu (TCE)

  Affiliation Department of Pharmacology and Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  https://orcid.org/0000-0002-4601-2117

  ⨯