Network propagation of rare variants in Alzheimer’s disease reveals tissue-specific hub genes and communities

• Marzia Antonella Scelsi ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: marzia.scelsi.15@ucl.ac.uk

  Affiliation Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

  https://orcid.org/0000-0002-5861-6452

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• Valerio Napolioni,

  Roles Data curation, Writing – review & editing

  Current address: Genomic and Molecular Epidemiology (GAME) Lab, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy

  Affiliation Functional Imaging in Neuropsychiatric Disorders (FIND) Lab, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America

  https://orcid.org/0000-0002-4378-6838

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• Michael D. Greicius,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Functional Imaging in Neuropsychiatric Disorders (FIND) Lab, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America

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• Andre Altmann,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

  https://orcid.org/0000-0002-9265-2393

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• for the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Alzheimer’s Disease Sequencing Project (ADSP)

  ¶Membership for the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Alzheimer’s Disease Sequencing Project (ADSP) is listed in the Supplementary information S2 Text.

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