-
Loading metrics
A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness
-
T. J. Sego ,
Contributed equally to this work with: T. J. Sego, Josua O. Aponte-Serrano
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: tjsego@iu.edu
Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America
⨯ -
Josua O. Aponte-Serrano ,
Contributed equally to this work with: T. J. Sego, Josua O. Aponte-Serrano
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America
⨯ -
Juliano Ferrari Gianlupi,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing
Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America
⨯ -
Samuel R. Heaps,
Roles Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America
⨯ -
Kira Breithaupt,
Roles Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing
Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Cognitive Science Program, Indiana University, Bloomington, Indiana, United States of America
⨯ -
Lutz Brusch,
Roles Conceptualization, Methodology, Validation, Writing – original draft, Writing – review & editing
Affiliation Center for Information Services and High Performance Computing (ZIH), Technische Universität, Dresden, Germany
⨯ -
Jessica Crawshaw,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia
⨯ -
James M. Osborne,
Roles Conceptualization, Methodology, Validation, Writing – original draft, Writing – review & editing
Affiliation School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia
⨯ - Ellen M. Quardokus,
-
Richard K. Plemper,
Roles Writing – review & editing
Affiliation Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, United States of America
⨯ -
James A. Glazier
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliations Department of Intelligent Systems Engineering, Indiana University, Bloomington, Indiana, United States of America, Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America
⨯
https://orcid.org/0000-0002-4274-656X
A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness
- T. J. Sego,
- Josua O. Aponte-Serrano,
- Juliano Ferrari Gianlupi,
- Samuel R. Heaps,
- Kira Breithaupt,
- Lutz Brusch,
- Jessica Crawshaw,
- James M. Osborne,
- Ellen M. Quardokus,
- Richard K. Plemper
-
- Published: December 21, 2020
- https://doi.org/10.1371/journal.pcbi.1008451