Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus

• Jingwei Ma,

  Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-6232-4938

  ⨯
• Myan Do,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliation Department of Cellular and Molecular Medicine, University of California, San Diego Medical School, San Diego, California, United States of America

  https://orcid.org/0000-0001-5892-6859

  ⨯
• Mark A. Le Gros,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Visualization

  Affiliations Department of Anatomy, University of California, San Francisco, San Francisco, California, United States of America, National Center for X-ray Tomography, Lawrence Berkeley National Lab, Berkeley, California, United States of America

  ⨯
• Charles S. Peskin,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Courant Institute of Mathematical Sciences, New York University, New York, New York, United States of America

  https://orcid.org/0000-0003-3749-9864

  ⨯
• Carolyn A. Larabell,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Anatomy, University of California, San Francisco, San Francisco, California, United States of America, National Center for X-ray Tomography, Lawrence Berkeley National Lab, Berkeley, California, United States of America

  https://orcid.org/0000-0002-6262-4789

  ⨯
• Yoichiro Mori,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Mathematics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0002-4851-5148

  ⨯
• Samuel A. Isaacson

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: isaacson@math.bu.edu

  Affiliation Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-7543-8619

  ⨯