Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration

Joseph H. R. Hetmanski; Matthew C. Jones; Fatima Chunara; Jean-Marc Schwartz; Patrick T. Caswell

doi:10.1371/journal.pcbi.1008213

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Open Access

Peer-reviewed

Research Article

Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration

Joseph H. R. Hetmanski ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: joseph.hetmanski@manchester.ac.uk (JHRH); patrick.caswell@manchester.ac.uk (PTC)

Affiliation Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom

https://orcid.org/0000-0002-1493-351X

⨯
Matthew C. Jones,

Roles Conceptualization, Resources, Writing – review & editing

Affiliation Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom

https://orcid.org/0000-0003-4723-3277

⨯
Fatima Chunara,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom
⨯
Jean-Marc Schwartz,

Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom

https://orcid.org/0000-0002-6472-0184

⨯
Patrick T. Caswell

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: joseph.hetmanski@manchester.ac.uk (JHRH); patrick.caswell@manchester.ac.uk (PTC)

Affiliation Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom

https://orcid.org/0000-0002-2633-2324

⨯

Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration

Joseph H. R. Hetmanski,
Matthew C. Jones,
Fatima Chunara,
Jean-Marc Schwartz,
Patrick T. Caswell

Published: March 10, 2021
https://doi.org/10.1371/journal.pcbi.1008213

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