Pseudocell Tracer—A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination

• Derek Reiman ,

  Contributed equally to this work with: Derek Reiman, Godhev Kumar Manakkat Vijay, Heping Xu

  Roles Formal analysis, Methodology, Software

  Affiliation University of Illinois at Chicago, Department of Bioengineering, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-7955-3980

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• Godhev Kumar Manakkat Vijay ,

  Contributed equally to this work with: Derek Reiman, Godhev Kumar Manakkat Vijay, Heping Xu

  Roles Methodology, Validation

  Affiliation University of Pittsburgh, Center for Systems Immunology, Departments of Immunology and Computational and Systems Biology, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0003-3833-3057

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• Heping Xu ,

  Contributed equally to this work with: Derek Reiman, Godhev Kumar Manakkat Vijay, Heping Xu

  Roles Conceptualization, Resources, Validation

  Affiliations Key Laboratory of Growth Regulation and Translation Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China

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• Andrew Sonin,

  Roles Methodology

  Affiliation Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia

  https://orcid.org/0000-0003-1000-7102

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• Dianyu Chen,

  Roles Methodology

  Affiliations Key Laboratory of Growth Regulation and Translation Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China

  https://orcid.org/0000-0002-4217-2279

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• Nathan Salomonis,

  Roles Formal analysis

  Affiliation Division of Biomedical Informatics, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  https://orcid.org/0000-0001-9689-2469

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• Harinder Singh ,

  Roles Conceptualization, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: harinder@pitt.edu (HS); aakhan@uchicago.edu (AAK)

  Affiliation University of Pittsburgh, Center for Systems Immunology, Departments of Immunology and Computational and Systems Biology, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0002-6330-8526

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• Aly A. Khan

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: harinder@pitt.edu (HS); aakhan@uchicago.edu (AAK)

  Affiliation University of Chicago, Department of Pathology, Chicago, Illinois, United States of America

  https://orcid.org/0000-0003-3933-8538

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