Implications of localized charge for human influenza A H1N1 hemagglutinin evolution: Insights from deep mutational scans

• Chadi M. Saad-Roy ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: csaadroy@princeton.edu (CMSR); grenfell@princeton.edu (BTG)

  Affiliation Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

  http://orcid.org/0000-0002-2217-3071

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• Nimalan Arinaminpathy,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0002-0412-150X

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• Ned S. Wingreen,

  Roles Investigation, Writing – review & editing

  Affiliations Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

  http://orcid.org/0000-0001-7384-2821

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• Simon A. Levin,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

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• Joshua M. Akey,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

  http://orcid.org/0000-0002-4411-1330

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• Bryan T. Grenfell

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: csaadroy@princeton.edu (CMSR); grenfell@princeton.edu (BTG)

  Affiliations Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America, Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, New Jersey, United States of America, Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

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