In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

Shane D. Anderson; Asna Tabassum; Jae Kyung Yeon; Garima Sharma; Priscilla Santos; Tik Hang Soong; Yin Win Thu; Isaac Nies; Tomomi Kurita; Andrew Chandler; Abdelaziz Alsamarah; Rhye-Samuel Kanassatega; Yun L. Luo; Wesley M. Botello-Smith; Bradley T. Andresen

doi:10.1371/journal.pcbi.1007719

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Open Access

Peer-reviewed

Research Article

In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

Shane D. Anderson,

Roles Data curation, Formal analysis, Investigation, Resources, Visualization, Writing – original draft

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America
⨯
Asna Tabassum,

Roles Data curation, Investigation, Resources, Visualization

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0002-6020-5652

⨯
Jae Kyung Yeon,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0002-6170-3848

⨯
Garima Sharma,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America
⨯
Priscilla Santos,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0002-1516-8194

⨯
Tik Hang Soong,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0001-8722-0839

⨯
Yin Win Thu,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America
⨯
Isaac Nies,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0002-3232-358X

⨯
Tomomi Kurita,

Roles Investigation

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America
⨯
Andrew Chandler,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0002-2527-0125

⨯
Abdelaziz Alsamarah,

Roles Software

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America
⨯
Rhye-Samuel Kanassatega,

Roles Investigation, Resources

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0001-9007-6524

⨯
Yun L. Luo ,

Roles Resources, Supervision, Writing – review & editing

* E-mail: luoy@westernu.edu (YLL); wbotellosmith@westernu.edu (WMB-S); bandresen@westernu.edu (BTA)

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0003-3581-754X

⨯
Wesley M. Botello-Smith ,

Roles Data curation, Resources, Software, Supervision, Visualization

* E-mail: luoy@westernu.edu (YLL); wbotellosmith@westernu.edu (WMB-S); bandresen@westernu.edu (BTA)

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0003-2691-4460

⨯
Bradley T. Andresen

Roles Conceptualization, Formal analysis, Project administration, Writing – review & editing

* E-mail: luoy@westernu.edu (YLL); wbotellosmith@westernu.edu (WMB-S); bandresen@westernu.edu (BTA)

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

https://orcid.org/0000-0002-3948-7456

⨯

In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

Shane D. Anderson,
Asna Tabassum,
Jae Kyung Yeon,
Garima Sharma,
Priscilla Santos,
Tik Hang Soong,
Yin Win Thu,
Isaac Nies,
Tomomi Kurita,
Andrew Chandler

Published: November 25, 2020
https://doi.org/10.1371/journal.pcbi.1007719

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