Bioinformatics analysis of whole slide images reveals significant neighborhood preferences of tumor cells in Hodgkin lymphoma

• Jennifer Hannig ,

  Contributed equally to this work with: Jennifer Hannig, Hendrik Schäfer

  Roles Data curation, Formal analysis, Investigation, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation KITE - Kompetenzzentrum für Informationstechnologie, Technische Hochschule Mittelhessen, Friedberg, Germany

  http://orcid.org/0000-0002-2789-5540

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• Hendrik Schäfer ,

  Contributed equally to this work with: Jennifer Hannig, Hendrik Schäfer

  Roles Data curation, Formal analysis, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Molecular Bioinformatics, Institute of Computer Science, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

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• Jörg Ackermann,

  Roles Data curation, Formal analysis, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Molecular Bioinformatics, Institute of Computer Science, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

  ⨯
• Marie Hebel,

  Roles Investigation, Software

  Affiliation Institute of Biochemistry II, Johann Wolfgang Goethe-University, University Hospital Frankfurt am Main, Frankfurt am Main, Germany

  ⨯
• Tim Schäfer,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization

  Affiliation Department of Child and Adolescent Psychiatry, University Hospital Frankfurt am Main, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

  http://orcid.org/0000-0002-3683-8070

  ⨯
• Claudia Döring,

  Roles Data curation, Formal analysis, Supervision

  Affiliation Dr. Senckenberg Institute of Pathology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

  ⨯
• Sylvia Hartmann,

  Roles Data curation, Investigation, Supervision, Validation

  Affiliation Dr. Senckenberg Institute of Pathology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

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• Martin-Leo Hansmann ,

  Roles Conceptualization, Investigation, Project administration, Supervision, Writing – review & editing

  ¶‡ These authors share last authorship on this work.

  Affiliation Consultation and reference center for lymph node pathology at Dr. Senckenberg Institute of Pathology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

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• Ina Koch

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ina.koch@bioinformatik.uni-frankfurt.de

  ¶‡ These authors share last authorship on this work.

  Affiliation Molecular Bioinformatics, Institute of Computer Science, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

  http://orcid.org/0000-0002-3621-003X

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