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Differential regulatory network-based quantification and prioritization of key genes underlying cancer drug resistance based on time-course RNA-seq data
- Jiajun Zhang ,
- Wenbo Zhu ,
- Qianliang Wang,
- Jiayu Gu,
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L. Frank Huang ,
Roles Formal analysis, Investigation, Software, Visualization, Writing – review & editing
* E-mail: Frank.Huang@cchmc.org, hleicug@gmail.com (LFH); sunxq6@mail.sysu.edu.cn, xiaoqiangsun88@gmail.com (XS)
Affiliations Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America
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Xiaoqiang Sun
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: Frank.Huang@cchmc.org, hleicug@gmail.com (LFH); sunxq6@mail.sysu.edu.cn, xiaoqiangsun88@gmail.com (XS)
Affiliation Department of Medical Informatics, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China; Key Laboratory of Tropical Disease Control (Sun Yat-Sen University), Chinese Ministry of Education, Guangzhou, Guangdong, China
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http://orcid.org/0000-0002-0322-6078
Differential regulatory network-based quantification and prioritization of key genes underlying cancer drug resistance based on time-course RNA-seq data
- Jiajun Zhang,
- Wenbo Zhu,
- Qianliang Wang,
- Jiayu Gu,
- L. Frank Huang,
- Xiaoqiang Sun
- Published: November 4, 2019
- https://doi.org/10.1371/journal.pcbi.1007435