Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data

• Allison L. Hicks ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: allison_hicks@g.harvard.edu (ALH); ygrad@hsph.harvard.edu (YHG)

  Affiliation Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0003-1372-1301

  ⨯
• Nicole Wheeler,

  Roles Methodology, Writing – review & editing

  Affiliation Centre for Genomic Pathogen Surveillance, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom

  http://orcid.org/0000-0003-4599-9164

  ⨯
• Leonor Sánchez-Busó,

  Roles Methodology, Writing – review & editing

  Affiliations Centre for Genomic Pathogen Surveillance, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom, Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  ⨯
• Jennifer L. Rakeman,

  Roles Resources, Writing – review & editing

  Affiliation Public Health Laboratory, Division of Disease Control, New York City Department of Health and Mental Hygiene, New York, New York, United States of America

  ⨯
• Simon R. Harris,

  Roles Writing – review & editing

  Affiliation Microbiotica Ltd, Biodata Innovation Centre, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom

  http://orcid.org/0000-0003-1512-6194

  ⨯
• Yonatan H. Grad

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: allison_hicks@g.harvard.edu (ALH); ygrad@hsph.harvard.edu (YHG)

  Affiliations Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America, Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0001-5646-1314

  ⨯